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. 2020 Mar 10;10:197. doi: 10.3389/fonc.2020.00197

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Copyright © 2020 Yang, Men, Xue, Jiang and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Forest plot of diarrhea in patients treated with immune checkpoint inhibitor plus chemotherapy vs. chemotherapy. (B) Funnel plot of diarrhea in patients treated with immune checkpoint inhibitor plus chemotherapy vs. chemotherapy. ICI, immune checkpoint inhibitor; CTLA-4, cytotoxic T lymphocyte antigen-4; PD-L1, programmed death ligand 1; PD-1, programmed death 1; SE, standard error; RR, risk ratio.