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. 2020 Mar 10;11:252. doi: 10.3389/fphar.2020.00252

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Copyright © 2020 Chan, Cheung, Zhang, Fu, Tan, Norimoto, Wang and Feng.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Quality control of HLJDD. (A) Showed the representative chromatogram of HLJDD extracts. Three major compounds, berberine, baicalin and geniposide, were identified on the chromatogram by matching the retention time and UV spectrum with those of reference compounds; (B) showed the inter-batches quality of HLJDD as represented by the relative contents of berberine, baicalin and geniposide; (C) showed that stability of HLJDD over 24-month storage as represented by the relative contents of berberine, baicalin, and geniposide.