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. 2020 Mar 10;14:35. doi: 10.3389/fnbeh.2020.00035

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Copyright © 2020 Kontaris, East and Wilson.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic representation of the primary (direct input from the olfactory bulb) and secondary (one synapse beyond primary regions) olfactory network. Shading identifies the same regions as shown in the affectome (Figure 2). This remarkably tight, often reciprocal relationship between early stages of the olfactory system and the connectome may promote odor modulation of mood and emotion. Abbreviations: AON, anterior olfactory nucleus; aPCX, anterior piriform cortex; BLA, basolateral amygdala; CoA, cortical nucleus of the amygdala; HIPP, hippocampus; HLDB, horizontal limb of the diagonal band; HYP, hypothalamus; LEC, lateral entorhinal cortex; MDT, mediodorsal thalamus; NAc, nucleus accumbens; OB, olfactory bulb; OFC, orbitofrontal cortex; OT, olfactory tubercle; PFC, prefrontal cortex; pPCX, posterior piriform cortex.