Figure 1.

Nerve injury differentially alters the expression levels of CB₁Rs and CB₂Rs in the DRG and spinal cord. A, real-time PCR data showing the mRNA level of CB₁Rs in the rat DRG at days 5, 10, and 21 after sham or SNL surgery. B, the mRNA level of CB₁Rs in the rat dorsal spinal cord 21 days after sham or SNL surgery. C, real-time PCR data showing the mRNA level of CB₂Rs in the rat DRG on days 5, 10, and 21 after sham or SNL surgery. D, the mRNA level of CB₂Rs in the rat dorsal spinal cord 21 days after sham or SNL surgery. Data are shown as means ± S.E. (n = 6 rats/group). Gapdh was used as an endogenous control, and the mean value in the sham group was set to 1. *, p < 0.05; ***, p < 0.001 compared with the sham group at the same time point. Two-way ANOVA followed by Tukey post hoc test was used for A and C. Two-tailed Student's t test was used for B and D.