| Methods |
Randomized, placebo‐controlled, double‐blind trial |
| Participants |
946 children aged 6 to 90 months, in the community |
| Interventions |
100,000 IU of vitamin A for children aged 6 to 11 months or 200,000 IU of vitamin A for older children every 4 months for 2 years |
| Outcomes |
Death |
| Notes |
Quality score 5 |
| Risk of bias |
| Bias |
Authors' judgement |
Support for judgement |
| Random sequence generation (selection bias) |
Low risk |
The study area was divided into 185 small geographic units, each comprising 30 to 77 compounds. The units were randomized to receive either vitamin A or placebo using a method of randomization of clusters |
| Allocation concealment (selection bias) |
Low risk |
Adequate |
| Blinding (performance bias and detection bias)
All outcomes |
Low risk |
Double‐blinded |
| Blinding of participants and personnel (performance bias)
All outcomes |
Low risk |
|
| Blinding of outcome assessment (detection bias)
All outcomes |
Low risk |
|
