Table 3.

Lesions by CT, necropsy, microbiology, and scans

Pigs		1	2	3	4	5	6	7	8	9	10
Lesions and findings
Osteomyelitis (OM)	CT1	5	0	3	3	5	1	2	0	3	1
	Necropsy	4	0	3	3	3	1	2	0	22	03
	Microbiology4	+	n.t.5	+	+	+	+	+	n.t.	n.t.	+6
	[18F]FDG1	5	0	3	3	5	1	2	0	3	1
	[99mTc]IL81	2	0	0	3	4	1	2	0	3	1
Inoculation site abscess	CT7	-	+	-	+	+	+	+	-	+	(+)
	Necropsy	-	-7	-	+	+	+	+	-	+	+
	Mircobiology4	n.t.	-	n.t.	+	+	+	+	n.t.	+	+8
	[18F]FDG	-	(+)	-	-	(+)	+	+	-	+	(+)
	[99mTc]IL8	-	-	-	-	(+)	+	+	-	(+)	-
Lungs with pneumonia	CT	-	-	+	-	-	-	+	-	-	+
	Necropsy	-9	-9	+10	-	-11	-9	+	-11	-11	+
	Microbiology	-	-	-	-	-	-	+	-	-	+12
	[18F]FDG	(+)	-	-	-	-	(+)	+	-	+	+
	[99mTc]IL8	(+)	+	(+)	-	-	(+)	+	(+)	-	-

[^99mTc]IL8 and [¹⁸F]FDG accumulation in OM and abscesses in the right inguinal region and in neck muscles (Temgesic injections). Pig 2 and 8 are marked by bold italic as these pigs did not develop OM. Some data from the pigs have been published previously: pigs 1, 3, 4, 6, 7, 9, 10 [53]. +; identified. (+); identified, but more difficult to detect.

¹Number of OM lesions sites; thus by Computed Tomography (CT), [¹⁸F]FDG and [^99mTc]IL-8 OM lesions were defined by location, not the number, i.e. presence in distal femur, proximal tibia, distal tibia, proximal fibula, proximal metatarsal bone, distal metatarsal bone, proximal phalanx, and/or distal phalanx; in pig no 1 both tracers additionally accumulated in the left distal femur (no osteomyelitis), in left site lymph nodes, and in an abscess next to the calcaneus, but the antibiotic sensitivity indicated that S. aureus from the abscess belonged to another strain, different from the inoculated;

²one additional OM lesion found by histology;

³two OM lesions found by histology;

⁴reisolation of S. aureus from OM and/or periosseous abscesses;

⁵n.t. not tested;

⁶OM positive by microbiology and immunohistochemistry for S. aureus;

⁷seroma identified;

⁸Another strain i.e. MRSA;

⁹atelectasis and edema;

¹⁰bronchopneumonia;

¹¹atelectasis;

¹²Not the inoculated S. aureus strain and not MRSA.