Table 3. Effects of dehydroepiandrosterone treatment in different domains.

Domain	Beneficial/Adverse effects	References
Body composition	• Inconsistent evidence with regard to bone mineral density, bone health and metabolism	[39,81,82,83,84]
	• Reduction of fat mass in older men
Cognition	• Improvement of episodic memory in one study	[85,86,87,88,89,90]
	• Insufficient evidence to suggest beneficial effects
Mood and depressive disorders	• Some studies suggest mood enhancing effects	[64,85,88,91,92,93,94]
	• Insufficient evidence to suggest beneficial effects
Sexual functioning	• Some studies report positive effects, other no effects	[39,74,81,95,96,97]
	• Insufficient evidence to suggest beneficial effects