Table 3.
Bivariate analysis and hierarchical Cox final regression model for independent factors for ARDS
| Bivariate analysis | Cox final regression model | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Hazard ratio | Confidence interval 95% | P | Hazard ratio | Confidence interval 95% | P | |
| 1st Hierarchy - ICU admission variables | ||||||
| Age | 1.02 | 1.01-1.04 | 0.009 | 1.04 | 1.02-1.06 | < 0.001 |
| TBSA | 1.00 | 0.98-1.02 | 0.996 | |||
| 3rd degree burn | 1.56 | 0.75-3.24 | 0.233 | |||
| Inhalation Injury | 1.90 | 0.98-3.67 | 0.058 | 2.50 | 1.24-5.02 | 0.010 |
| Masculine sex | 1.27 | 0.65-2.49 | 0.490 | |||
| Chemical burn | 7.80 | 1.04-58.24 | 0.045 | |||
| Thermal burn | 1.94 | 0.46-8.08 | 0.364 | |||
| 2nd Hierarchy - Interventions and outcome | ||||||
| Vasopressor drug | 1.16 | 0.60-2.26 | 0.660 | |||
| Red blood cell concentrate | 0.47 | 0.24-0.92 | 0.027 | |||
| AKI | 1.61 | 0.81-3.21 | 0.176 | |||
| 3rd Hierarchy - Accumulated fluid balance | ||||||
| Accumulated 24 hours | 1.00 | 0.99-1 | 0.965 | |||
| Accumulated 48 hours | 1.00 | 0.99-1 | 0.685 | |||
| 4th Hierarchy - Ventilatory variables | ||||||
| Current volume day 1 | 1.03 | 0.87-1.22 | 0.718 | |||
| Static compliance day 1 | 0.99 | 0.96-1.01 | 0.324 | 0.97 | 0.94-0.99 | 0.030 |
| Driving pressure day 1 | 1.03 | 0.94-1.13 | 0.501 | |||
Legend 1: ARDS - acute respiratory distress syndrome; ICU - intensive care unit; TBSA - total burned body surface area; AKI - acute kidney injury.