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. 2020 Feb 17;12(2):167. doi: 10.3390/pharmaceutics12020167

Table 2.

Functions and concentrations of transport inhibitors. MβCD, methyl-β-cyclodextrin.

Transport Inhibitors Functions Concentrations
Endocytosis Process
chlorpromazine inhibitor of clathrin-related route 20 μg/mL
dynasore block the formation of a pinched-off vesicle 30 μg/mL
MβCD caveolae (or lipid raft)-mediated route 2.5 mg/mL
EIPA inhibit the macropinocytosis pathway 20 μg/mL
Endocellular Transport Process
monensin inhibit acidification of endosomes 30 μg/mL
nocodazole inhibitor of microtubules 10 μg/mL
bafilomycin A1 inhibit the maturation process of lysosomes 100 μM