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Dissolution profile of ABN401 in pH 1.2 of (a) physical blend in capsule with and without bulking agent (starch and MCC) at 50 mg, (b) a granulated blend in capsule at two doses (50 mg and 200 mg). (c) Dissolution profile of ABN401 at various pH values in gelatin capsule with optimized granulation at 50 mg (dotted) and 200 mg (solid) dose and (d) SEM image of the granulated blend.
