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In vivo therapeutic efficacy of ABN401 in NSCLC patient-derived xenograft (PDX) models. (a) Growth curves of LU0858 NSCLC tumors in ABN401 and/or erlotinib-treated mice. Dose-dependent anti-tumor activity of ABN401 and in vivo anti-tumor activity of erlotinib alone or in combination with ABN401 is shown. P-values: *** < 0.001. (b) Tumor growth inhibition values on day 21 are shown.
