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. 2020 Feb 3;12(2):127. doi: 10.3390/pharmaceutics12020127

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Metabolic profiles of HSG4112 in rat plasma after oral administration (100 mg/kg/day, 28th day, n = 3). (A) Plot for time-peak area of HSG4112 and its metabolites. (B) Plot for time-plasma concentration of HSG4112, M1c-1 and M1c-2. (C) Area under curve values of HSG4112 and its metabolites calculated from (A).

Metabolic profiles of HSG4112 in rat plasma after oral administration (100 mg/kg/day, 28th day, n = 3). (A) Plot for time-peak area of HSG4112 and its metabolites. (B) Plot for time-plasma concentration of HSG4112, M1c-1 and M1c-2. (C) Area under curve values of HSG4112 and its metabolites calculated from (A).