Table 3.

Canonical pathways and targets associated with the network shown in Figure 2.

Canonical Pathway	Targets	Z-Score 1	p-Value
Protein ubiquitination	19S proteasome; 26S proteasome; ATPase; CRYAA/CRYAA2; DNAJB2; Hsp70; HSP; HSPH1; MHC CLASS I (family); PSMB4; PSMC2; PSMD4; PSMD9; PSMD13; PSMD; Ubiquitin	N/A	2.86·10−6
Clathrin-mediated endocytosis	ATPase; HSP; HGS; HSP70; Ubiquitin	N/A	4.14·10−9
Synaptogenesis signaling	ATPase; HSP70; HSP; MAPK	1.1	2.20·10−4

¹ Positive value: Activation of the canonical pathway; N/A: No prediction can be made.