Table 1:

Criteria and Definitions from the Web Survey

Criterion	Definition
Chemical properties	Properties of a chemical that contribute to the exposure potential for human beings.
Physical hazard potential	Assessed in terms of flammability and reactivity. Thresholds as established by NFPA 0–7.
Persistence	Assessed in terms of chemical half-lives in soil, sediment, air, and water. Thresholds established by (1) EPA: Design for the Environment Program Alternatives; (2) Clean Production Action: The Green for Safer Chemicals Version 1.0.
ADME	Assessed in terms of the human body's ability to absorb (A), distribute (D), metabolize (M), and excrete (E) the chemical. Thresholds and values derived using QikProp v3.0, based on 24-hour exposure period.
Bioaccumulation	Assessed in terms of bioconcentration factor (BCF), octanol–water partition coefficient (Kow), and/or molecular weight. Thresholds established by (1) EPA: Design for the Environmental Program Alternatives; (2) Clean Production Action: The Green Screen for Safer Chemicals Version 1.0; and (3) Euro Chlor: Bioaccumulation: Definitions and Implications.
Life cycle properties	The characteristics of a chemical's use throughout its life, ranging from production to product end-of-life.
Production	Factors in production that create potential for exposure in human beings.
Consumer use	Factors in consumer use that create potential for exposure in human beings.
Disposal	Factors in disposal that create potential for exposure in human beings.
Human use metrics	Factors associated with exposure potential for each of the life cycle stages.
Ubiquity	How widespread the use of the chemical is in the (production, consumer use, disposal) life cycle area.
Environment	The external environment of use in the (production, consumer use, disposal) life cycle area.
Subject	Characteristics about the expected subject (user) of the chemical in the (production, consumer use, disposal) life cycle stage.
Activity	The physical activities when using the chemical that influence exposure in the (production, consumer use, disposal) life cycle area.

Note: Subcriteria are indented.