Skip to main content
. 2020 Feb 5;105(4):e1358–e1376. doi: 10.1210/clinem/dgaa049

Table 3.

Exposure to Treatment and Adherence to Treatment

a) Main period
Somapacitan Daily GH Placebo
(N = 120) (N = 119) (N = 61)
Exposure to treatment, days
 Mean 232 (36.2) 226 (48.0) 228 (36.1)
 Median 238 238 238
Treatment dose, mg, mean (SD) 2.56 (1.48) mg/week Equivalent to 0.37 mg/day 0.33 (0.19) mg/day Equivalent to 2.31 mg/week 2.20 (0.74) mg/week Equivalent to 0.31 mg/day
Mean adherence, % 95.5 90.6 93.9
b) Extension period
Somapacitan/ Somapacitan Daily GH/ Daily GH Placebo/ Somapacitan Daily GH/ Somapacitan
(N = 114) (N = 52) (N = 55) (N = 51)
Exposure to treatment, days
 Mean 355 (52.4) 349 (48.8) 357 (40.4) 343 (76.6)
 Median 364 364 364 364
Treatment dose in extension, mg, mean (SD) 2.35 (1.30) mg/week Equivalent to 0.34 mg/day 0.28 (0.16) mg/day Equivalent to 1.96 mg/week 2.61 (1.40) mg/week Equivalent to 0.37 mg/day 2.66 (1.37) mg/week Equivalent to 0.38 mg/day
Mean adherence during extension, % 94.7 91.9 89.8 94.7