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. 2020 Feb 19;12(2):175. doi: 10.3390/pharmaceutics12020175

Table 1.

Solubility of KY19382 in selected excipients.

Function in Formulation Vehicles Solubility (mg/mL) p-Value
Oils S1 Olive oil 0.83 ± 0.02 0.0312
S2 Sunflower oil 1.35 ± 0.98 0.0182
Surfactants S3 Kolliphor® EL 5.4 ± 0.95 0.0031
S4 Tween 20 4.58 ± 0.13 0.0269
S5 Tween 80 4.92 ± 0.23 0.0005
Co-surfactants S6 Transcutol P 1.15 ± 0.87 0.0443
S7 Propylene glycol 0.25 ± 0.03 0.0052
S8 PEG 400 3.1 ± 0.46 0.0003