Table 1.
Function in Formulation | Vehicles | Solubility (mg/mL) | p-Value | |
---|---|---|---|---|
Oils | S1 | Olive oil | 0.83 ± 0.02 | 0.0312 |
S2 | Sunflower oil | 1.35 ± 0.98 | 0.0182 | |
Surfactants | S3 | Kolliphor® EL | 5.4 ± 0.95 | 0.0031 |
S4 | Tween 20 | 4.58 ± 0.13 | 0.0269 | |
S5 | Tween 80 | 4.92 ± 0.23 | 0.0005 | |
Co-surfactants | S6 | Transcutol P | 1.15 ± 0.87 | 0.0443 |
S7 | Propylene glycol | 0.25 ± 0.03 | 0.0052 | |
S8 | PEG 400 | 3.1 ± 0.46 | 0.0003 |