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Schematic representation of liposomes, polymeric nanoparticles and extracellular vesicles. Carriers with their main components and the type of miR219a-5p they were loaded with. Liposomes and polymeric nanoparticles were loaded with synthetic microRNA. In contrast, extracellular vesicles (EVs) contained biologically produced microRNA. Polymeric nanoparticles and liposomes were also loaded with a dye (coumarin and DiOC18, respectively) to perform up-take studies.
