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. 2020 Feb 12;12(2):150. doi: 10.3390/pharmaceutics12020150

Figure 14.

Figure 14

Contour profiler showing the influence of the interaction of screw speed and feed rate on the predicted PRX amount using the PLS model. The red line indicates the predicted PRX content of 14.45% w/w. The black cross marks the optimised extruder parameters. The black dashed lines indicate the upper and lower limits defined respectively 14.75 and 14.15% w/w of PRX.