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. 2020 Feb 20;12(2):131. doi: 10.3390/toxins12020131

Table 4.

Mortality at 3 h, 6 h, and 24 h of mice injected with Bungarus multicinctus venom and treated with Varespladib (LY333013) (VAR) orally at various time intervals a.

Treatment Deaths/Total at 3 h Deaths/Total at 6 h Deaths/Total at 24 h
Venom + PBS 4/4
Venom + VAR (0 min) 0/4 0/4 4/4
Venom + VAR (60 min) 0/4 0/4 4/4
Venom + VAR (0 min and 240 min) 0/4 0/4 4/4
Venom + VAR (60 min and 240 min) 0/4 0/4 4/4

a Groups of four mice received three LD50s of venom by the subcutaneous route and then, at the time intervals indicated, they were injected with either PBS i.v. (controls), or received LY333013 (10 mg/kg) by the oral route. Deaths were recorded at 3 h, 6 h, and 24 h.