Figure 7.

Effects of cathepsins inhibitors on caspases activity and cytochrome c release. (A) Impacts of cathepsin (L and D) inhibitors on cytochrome c distribution. The original pictures of Western blotting (with protein maker) are shown in Supplementary Materials (Figure S3). (B) Impacts of cathepsin inhibitors on caspase-9 activity. (C) Impacts of cathepsin inhibitors on caspase-3 activity. Significant tests from the corresponding controls (without Vip3Aa treatment) and densitometry of the protein bands are indicated by NS, not significant, * p < 0.05, ** p < 0.01, and *** p < 0.001.