Table 2.
IC50 values (means ± standard deviations in μg·mL−1) of sponge-associated cyanobacterial extracts TAU-MAC 0915, 1015, 1115, and 1215. Values not sharing a common letter among cell lines tested after ANOVA and Fisher’s LSD analysis (p < 0.05) are significantly different.
| IC50 (μg·mL−1) | p Value (ANOVA test) | Fisher’s LSD | |
|---|---|---|---|
| TAU-MAC 0915 | |||
| Skin fibroblasts | 28.76 ± 18.79 | 0.0149 | ab |
| MDA-MB-231 | 44.58 ± 2.99 | b | |
| MCF-7 | 9.68 ± 0.58 | c | |
| A-431 | 29.12 ± 1.37 | ab | |
| HT-29 | 26.45 ± 8.39 | ac | |
| TAU-MAC 1015 | |||
| Skin fibroblasts | 45.74 ± 18.40 | 0.0439 | a |
| MDA-MB-231 | 26.17 ± 7.41 | b | |
| MCF-7 | 20.53 ± 9.68 | b | |
| A-431 | 14.03 ± 1.48 | b | |
| HT-29 | 17.56 ± 0.69 | b | |
| TAU-MAC 1115 | |||
| Skin fibroblasts | 45.25 ± 3.76 | 0.0000 | a |
| MDA-MB-231 | 37.26 ± 1.44 | b | |
| MCF-7 | 14.88 ±4.55 | c | |
| A-431 | 15.86 ± 0.73 | c | |
| HT-29 | 18.39 ± 1.37 | c | |
| TAU-MAC 1215 | |||
| Skin fibroblasts | 112.58 ± 7.86 | 0.0102 | a |
| MDA-MB-231 | 65.64 ± 2.43 | b | |
| MCF-7 | 34.95 ± 8.71 | b | |
| A-431 | 42.66 ± 31.55 | b | |
| HT-29 | 55.38 ± 17.51 | b |