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. 2020 Feb 3;20:29. doi: 10.1186/s12906-020-2831-y

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© The Author(s). 2020

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Crocetin and its synthesized derivatives A、B inhibits cell proliferation in B16F10 cells. B16F10 cells were treated with different concentrations of crocetin and its synthesized derivatives A、B inhibits. After 24 h’ co-incubation at 37 °C, the cell survival rate was determined by MTT assays. Data represent mean ± SD. The results shown were reproduced at least 6 independent experiments. *** Indicates p < 0.001, ** indicates p < 0.01, and * indicates p < 0.05, for each treatment group versus solvent control group