Table 2.
Characteristics of systematic reviews included in the Evidence Mapping
| Systematic review | Search date | Population | Included studies | Studies design | Number of patients | Meta-analysis | Tool for risk of bias assessment | |||
|---|---|---|---|---|---|---|---|---|---|---|
| RCT | NRCT | UCT | Obs | |||||||
| ABO 2017 | November 2016 | Neurogenic urinary tract dysfunction in multiple sclerosis (MS). | 3 | 2 | 0 | 1 | 0 | 426 | Yes | Cochrane Risk of Bias |
| ANDREAE 2015 | April 2014 | Chronic neuropathic pain | 5 | 5 | 0 | 0 | 0 | 178 | Yes | Cochrane Risk of Bias |
| BALDINGER 2012 | February 2011 | Amyotrophic lateral sclerosis/ motor neuron disease | 1 | 1 | 0 | 0 | 0 | 22 | No | Cochrane Risk of Bias |
| BEGA 2014 | April 2014 | Parkinson Disease | 2 | 2 | 0 | 0 | 0 | 26 | No | American Academy of Neurology classification |
| BOYCHUCK 2015 | April 2013 | Chronic nonmalignant neuropathic pain | 13 | 13 | 0 | 0 | 0 | 771 | No | JADAD 5 |
| CAMPELL 2001 | October 1999 | Pain. | 8 | 6 | 0 | 0 | 2 | 222 | No | JADAD 5 |
| CURTIS 2009 | October 2008 | Gilles de la Tourette | 2 | 2 | 0 | 0 | 0 | 28 | No | CONSORT |
| DE SOUZA 2013 | December 2012 | Fibromyalgia | 2 | 2 | 0 | 0 | 0 | 69 | No | Jadad5, Cochrane |
| DESHPANDE 2015 | April 2014 | Chronic noncancer pain | 6 | 6 | 0 | 0 | 0 | 226 | No | JADAD 5 |
| FINNERUP 2015 | April 2013 | Neuropathic pain | 9 | 9 | 0 | 0 | 0 | 1310 | Yes | JADAD 5 |
| FITZCHARLES 2016a | April 2015 | Fibromyalgia, back pain, osteoarthritis, rheumatoid arthritis | 4 | 4 | 0 | 0 | 0 | 160 | No | Cochrane Risk of Bias |
| FITZCHARLES 2016b | January 2015 | Rheumatic diseases | 4 | 4 | 0 | 0 | 0 | 201 | No | Cochrane Risk of Bias |
| GLOSS 2014 | September 2013 | Epilepsy | 4 | 4 | 0 | 0 | 0 | 48 | No | Cochrane Risk of Bias |
| ISKEDIJAN 2006 | June 2006 | Neuropathic pain. | 7 | 7 | 0 | 0 | 0 | 298 | Yes | JADAD 5 |
| JAWAHAR 2013 | December 2012 | Multiple sclerosis patients. | 4 | 4 | 0 | 0 | 0 | 565 | Yes | Cochrane Risk of Bias |
| KHAISER 2016 | May /2016 | Pain | 11 | 9 | 0 | 1 | 1 | 420 | No | Own criteria |
| KOPPEL 2014 | November 2013 | Several neurologic conditions | 28 | 26 | 1 | 1 | 0 | 3567 | No | American Academy of Neurology classification |
| KRISHNAN 2009 | April 2008 | Dementia | 1 | 1 | 0 | 0 | 0 | 15 | No | Cochrane Risk of Bias |
| LAKHAN 2009 | April 2009 | Multiple Sclerosis-related spasticity | 6 | 6 | 0 | 0 | 0 | 481 | No | JADAD 5 |
| LANGHORST 2015 | March 2014 | Inflamatory Bowel Disease | 1 | 1 | 0 | 0 | 0 | 22 | No | Cochrane Risk of Bias |
| LUTGE 2013 | July 2012 | Patients infected with human immunodeficiency virus (HIV) | 7 | 7 | 0 | 0 | 0 | 330 | No | Cochrane Risk of Bias |
| LYNCH 2011 | September–October 2010 | Chronic pain | 18 | 18 | 0 | 0 | 0 | 766 | No | JADAD 7 |
| LYNCH 2015 | October 2014 | Chronic pain | 11 | 0 | 0 | 0 | 0 | 1185 | No | JADAD 7 |
| MACHADO 2008 | December 2006 | Cancer patients receiving chemotherapy | 30 | 30 | 0 | 0 | 0 | 1719 | Yes | JADAD |
| MARTIN 2009 | February 2008 | Chronic pain. | 18 | 18 | 0 | 0 | 0 | 809 | Yes | JADAD 5 |
| MEHTA 2015 | September 2015 | Pain post spinal cord injury | 2 | 2 | 0 | 0 | 0 | 29 | No | PEDRO |
| MEYER 2010 | 2008 | Acute phase of acquired brain injury | 2 | 2 | 0 | 0 | 0 | 928 | No | PEDRO |
| MÜCKE 2016 | April 2015 | Palliative medicine | 9 | 9 | 0 | 0 | 0 | 1561 | Yes | Cochrane Risk of Bias |
| OMS 2016 | September 2016 | Multiple sclerosis, chronic pain, HIV/AIDS, Dementia, Tourette syndrome and adults in chemotherapy. | 43 | 43 | 0 | 0 | 0 | 4586 | Yes | Cochrane Risk of Bias |
| OTERO-ROMERO 2016 | August 2013 | Multiple Sclerosis-related spasticity | 8 | 8 | 0 | 0 | 0 | No | EFNS scientific task forces | |
| PETZKE 2016 | November 2015 | Neuropathic pain syndromes | 15 | 15 | 0 | 0 | 0 | 1619 | Yes | Cochrane Risk of Bias |
| PILLIPS 2010 | February 2010 | Neuropathic pain in HIV patients | 2 | 2 | 0 | 0 | 0 | 89 | Yes | JADAD 7 |
| PILLIPS 2016 | December 2014 | Children and young people receiving chemotherapy | 4 | 4 | 0 | 0 | 0 | 78 | Yes | Cochrane Risk of Bias |
| RICHARDS 2012 | December 2010 | Pain in patients with rheumatoid arthritis | 1 | 1 | 0 | 0 | 0 | 58 | No | COChrane Risk of Bias |
| SHAKESPEARE 2003 | June 2003 | Multiple Sclerosis-related spasticity | 2 | 2 | 0 | 0 | 0 | 40 | No | Cochrane Risk of Bias |
| SMITH 2015 | January 2015 | Chemotherapy-induced nausea in cancer patients | 23 | 23 | 0 | 0 | 0 | 1326 | Yes | Cochrane Risk of Bias |
| SNEDECOR 2014 | June 2011 | Painful diabetic peripheral neuropathy | 1 | 1 | 0 | 0 | 0 | 30 | Yes | JADAD 5 |
| STEVENS 2017 | August 2016 | Acute pain. | 7 | 7 | 0 | 0 | 0 | 611 | No | Cochrane Risk of Bias |
| TEASELL 2010 | June 2009 | Spinal Cord Injury | 2 | 1 | 0 | 0 | 1 | 22 | No | PEDRO, Downs and Black checklist |
| TRAMER 2001 | August 2008 | Sickness induced by chemotherapy | 30 | 30 | 0 | 0 | 0 | 1366 | Yes | JADAD 5 |
| VAN DEN ELSEN 2014 | October 2013 | Older subjects. | 5 | 5 | 0 | 0 | 0 | 267 | No | Cochrane Risk of Bias |
| VOLZ 2016 | March 2015 | Inflammatory diseases, irritable bowel syndrome and chronic pancreatitis | 1 | 1 | 0 | 0 | 0 | 21 | No | Cochrane Risk of Bias |
| WANG 2008 | October 2007 | Safety of medical cannabis use. | 31 | 23 | 0 | 0 | 8 | 3107 | Yes | JADAD, Downs and Back checklist |
| WHITING 2015 | April 2015 | Chronic pain, spasticity, adults in chemotherapy, weight gain in HIV, sleep disorders, Tourette syndrome | 79 | 79 | 0 | 0 | 0 | 6462 | Yes | Cochrane Risk of Bias |