Table 1.
Characteristics of the included studies in the meta-analysis
| Studies | Study design | Age (treatment group) | Age (control group) | Sample size (female) | treatment Intervention | control Intervention | Main outcomes |
|---|---|---|---|---|---|---|---|
| Bao et al., 2005 [15] | RCT | 52.5 ± 11.6 | 51.4 ± 10.7 | 60(25) | A + C | C | 1.1、2、3、4、5 |
| Cao et al., 2013 [16] | RCT | 58.5 ± 14.6 | 55.5 ± 15.2 | 60(27) | A + C | C | 1.2、2 |
| Chen et al., 2013 [17] | RCT | NA | NA | 80 (−) | A + C | C | 1.1、2、3 |
| Chen et al., 2016 [18] | RCT | NA | NA | 56(28) | A + C | C | 1.1 |
| Duan et al., 2010 [19] | RCT | 62.20 ± 8.11 | 60.40 ± 7.85 | 40(13) | A + C | C | 1.2、8、11 |
| Guo et al., 2005 [20] | RCT | 54.23 ± 12.73 | 53.35 ± 11.73 | 60(23) | A + C | C | 1.1、2 |
| Hou et al., 2018 [21] | RCT | 61.25 ± 7.56 | 60.47 ± 8.41 | 126(47) | A + C + R | C + R | 1.1、3、12 |
| Jiang et al., 2010 [22] | RCT | NA | NA | 60 (−) | A + C | C | 1.1、2、6 |
| Li et al., 2006 [23] | RCT | 59.16 ± 12.89 | 62.82 ± 10.53 | 100(40) | A + C | C | 1.1、2 |
| Li et al., 2008 [24] | RCT | 56 ± 8 | 56 ± 6 | 96(40) | A + C | C | 1.1、2、6、12 |
| Li et al., 2009 [25] | RCT | 48.5 ± 5.2 | 45.7 ± 6.8 | 66(31) | A + C | C | 1.1、2、3、13、14 |
| Li et al., 2011 [6] | RCT | 62 ± 10 | 64 ± 9 | 120(54) | A + C | C | 1.1、3、7、10 |
| Tao et al., 2014 [26] | RCT | 62.7 | 60.5 | 54(18) | A + C | C | 1.1 |
| Wang et al., 2006 [27] | RCT | 59.32 ± 4.17 | 63.62 ± 5.03 | 64(25) | A + C | C | 1.1、10 |
| Wang et al., 2012 [28] | RCT | 60.5 | 59.5 | 128(54) | A + C | C | 1.1、2 |
| Wu et al., 2001 [29] | RCT | 63 ± 10 | 62 ± 9 | 46(11) | A + C | C | 1.1 |
| Zhang et al., 2005 [30] | RCT | NA | NA | 62(27) | A + C + O | C + O | 1.1、2、3、6、8 |
| Zhang et al., 2005 [31] | RCT | 63 ± 2 | 62 ± 2 | 95(30) | A + C | C | 1.1、2 |
| Zhang et al., 2017 [32] | RCT | 63.2 ± 6.3 | 63.5 ± 6.1 | 96(51) | A + C | C | 1.2、3、12 |
| Zhao et al., 2006 [33] | RCT | 60 ± 10 | 61 ± 7 | 60(27) | A + C | C | 1.1、8 |
| Zhao et al., 2008 [34] | RCT | 58.86 ± 9.37 | 62.64 ± 7.0 | 43(17) | A + C | C | 1.1、15 |
| Zhou et al., 2003 [35] | RCT | 66.8 ± 7.1 | 67.4 ± 6.5 | 58(21) | A + C | C | 1.1、3 |
| Zhu et al., 2006 [36] | RCT | NA | NA | 54(−) | A + C + R | C + R | 1.1、2、6 |
| Zou et al., 2009 [37] | RCT | 54.26 ± 8.78 | 55.35 ± 7.85 | 144(54) | A + C | C | 1.1、3 |
1.Neurological deficit score (1.1.CSS; 1.2.NIHSS); 2.Total effective rate; 3.Barthel; 4.CGRP; 5.ET; 6.ADL; 7.Symptom score of TCM; 8.NSE; 9.NDS; 10.Hematoma capacity; 11.Glasgow Coma Scale; 12.Fugl-Meyer; 13.S100;14.IGF-1; 15.IL-2
A = Acupuncture; C = Conventional therapy; R = Rehabilitation therapy; O = Other treatments; NA = Not available