Fig. 1.

Effect of germacrone on BGC823 cell proliferation and cell morphological changes. Cells were treated with germacrone at a serial of concentrations (0, 20, 40, 60, and 80 μM) for 12, 24, 48 and 72 h. a The chemical structure of germacrone. b Morphological observations BGC823 cells under optical microscopy at 200x magnification after 24 h treatment of germacrone in serial concentrations (0, 20, 40, 60, and 80 μM). c MTT assay showing the effect of germacrone on BGC823 cell proliferation cell. “*”: P < 0.05, “**”: P < 0.01