Table 2.
Summary of Findings
| Outcomes | Intervention (Mean ± SD) | Control (Mean ± SD) | No of Participants (studies) | Pooled Estimate | Ref | Quality of the evidence (GRADE) |
|---|---|---|---|---|---|---|
| HTP Dental Plaque. Follow-up: Short term | The mean short-term effects HTP in the intervention groups was 0.52 ± 0.33 | The mean short-term effects of NHTP in the control groups was 0.31 ± 0.21 | 712 (11 studies) | 1.95 higher (0.97, 2.93) | Fig. 2 A | ⊕ ⊕ ⊝⊝ low |
| HTP Dental Plaque. Follow-up: Long term | The mean long-term effects of HTP in the intervention groups was 1.02 ± 0.68 | The mean long-term effects of NHTP in the control groups was 0.80 ± 0.50 | 166 (4 studies) | 0.89 higher (−0.93, 2.72) | Fig. 2 A | ⊕ ⊕ ⊕⊝ moderate |
| HTP Gingival inflammation. Follow-up: Short term | The mean short-term effects of HTP in the intervention groups was 0.41 ± 0.30 | The mean short-term effects of NHTP in the control groups was 0.32 ± 0.19 | 410 (10 studies) | 0.09 higher (− 0.14, 0.00) | Fig. 2 B | ⊕ ⊕ ⊝⊝ low |
| HTP Gingival Inflammation. Follow-up: Long term | The mean long-term effects of HTP in the intervention groups was 0.50 ± 0.50 | The mean long-term effects of NHTP in the control groups was 0.43 ± 0.24 | 146 (3 studies) | 0.07 higher (− 0.23, 0.36) | Fig. 2 B | ⊕ ⊕ ⊝⊝ low |
| HMR Dental Plaque. Follow-up: Short term | The mean short-term effects of HMR in the intervention groups was 0.79 ± 0.49 | The mean short-term effects in of NHTP in the control groups was 0.91 ± 0.87 | 582 (6 studies) | 2.93 lower (−6.43, 0.58) | Fig. 3 A | ⊕ ⊕ ⊕⊝ moderate |
| HMR Dental Plaque Follow-up: Long term | The mean long terms effects of HMR in the intervention groups was 0.23 ± 0.51 | The mean long terms effects of NHTP in the control groups was 0.33 ± 0.49 | 285 (5 studies) | 2.61 lower (−4.42, −0.80) | Fig. 3 A | ⊕ ⊕ ⊕⊝ moderate |
| HMR Gingival Inflammation. Follow-up: Short term | The mean short-term effects of HMR in the intervention groups was 0.82 ± 0.34 | The mean short-term effects of NHTP in the control groups was 0.97 ± 0.54 | 582 (6 studies) | 0.15 lower (−0.32, 0.01) | Fig. 3 B | ⊕ ⊕ ⊝⊝ low |
| HMR Gingival inflammation. Follow-up: Long term | The mean long-term effects of HMR in the intervention groups was 0.22 ± 0.36 | The mean long-term effects of NHTP in the control groups was 0.31 ± 0.49 | 255 (5 studies) | 0.09 lower (−0.25, 0.08) | Fig. 3 B | ⊕ ⊕ ⊝⊝ low |
HTP herbal toothpaste, NHTP non herbal toothpaste, HMR herbal mouthrinse, NHMR non herbal mouthrinse, Short-term effect 4 weeks, Long Term effects 12 Weeks