Table 6.
One Month Study Blood Chemistry Control and 2014HP group by Sex ANOVA (bold – significant differences)
| Serum measure | GROUP main effect | SEX main effect | GROUP X SEX interaction | Special Notes *Report as p < .001 |
|---|---|---|---|---|
| F, p value (df 1,19) | F, p value (df 1, 19) | F, p value (df 1, 19) | ||
| Glucose (mg/dL) | 6.27, .02 | 5.47, .03 | 0.89, .36 | Placebo > 2014 HP & Females < Males |
| Urea Nitrogen (mg/dL) | 0.04, .84 | .12, .74 | 2.03, .17 | No significant interaction |
| Creatinine (mg/dL) | 0.13, .73 | 24.89, <.001 | 0.29, .60 | Females > Males |
| Sodium (mEq/L) | 2.07, .17 | 0.01, .93 | 2.65, .12 | No significant interaction |
| Potassium (mEq/L) | 27.70, <.001 | 25.14, <.001 | 29.88, <.001 |
differences between the groups is different for females and males. Females: Placebo > 2014 HP Males: Placebo < 2014 HP** |
| Chloride (mEq/L) | 0.07, .80 | 7.98, .01 | 0.03, .87 | Females > Males |
| Bicarbonate (mEq/L) | 0.90, .36 | 18.27, <.001 | 6.95, .02 |
differences between the groups is different for females and males. Females: Placebo < 2014 HP Males: Placebo > 2014 HP |
| Anion Gap (mEq/L) | 18.69, <.001 | 0.23, .64 | 2.83, .11 | Placebo < 2014 HP |
| Albumin (g/dL) | 0.17, .69 | 77.95, <.001 | 0.51, .49 | Females > Males |
| Total Protein (g/dL) | 1.42, .25 | 74.89, <.001 | 0.26, .62 | Females > Males |
| Globulin (g/dL) | 6.40, .02 | 16.81, .001 | 0.03, .87 | Placebo > 2014 HP** & Females > Males |
| Calcium (mg/dL) | 0.11, .74 | 45.25, <.001 | 0.91, .35 | Females > Males |
| Phosphorus (mg/dL) | 9.82, .005 | 14.87, .001 | 0.61, .45 | Placebo < 2014 HP & Females < Males |
| Cholesterol (mg/dL) | 0.02, .90 | 11.89, .003 | 0.08, .78 | Females < Males |
| Total Bilirubin (mg/dL) | 66.58, <.001 | 4.29, .052 | 4.29, .052 | Placebo < 2014 HP** |
| ALT (U/L) | 0.65, .43 | 21.51, <.001 | 0.20, .66 | Females < Males |
| ALP (U/L) | 1.04, .32 | 8.09, .01 | 3.00, .10 | Females < Males |
| GGT (U/L) | All values were “< 3” – no analyses conducted | |||
| CK (U/L) | 4.36, .05 | 6.75, .02 | 8.28, .01 |
differences between the groups is different for females and males. Females: Placebo < 2014 HP Males: Placebo > 2014 HP |
| Hemolysis (Mild to moderate hemolysis may cause false increases in direct bilirubin and AST measurement. Marked hemolysis can adversely affect all chemistry tests.) |
Overall Model Test - X2 = 9.04, df 3, p = .03 Binary logistic regression to predict hemolysis. Wald X2 statistic |
|||
| X2 = 0.11, df 1, p = .74 | X2 = 0.0, df 1, p = .99 | X2 = 0.0, df 1, p = 1.0 | ||
**HP group(s) was significantly (p < .05) different from Control Group