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. 2020 Mar 16;13:17. doi: 10.1186/s13072-020-00338-8

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Characterization of conserved DNMT1-dependent regions in the Human genome. a The percent span of the DNMT1-dependent regions in mouse covered by the identified human conserved regions. Pie chart represents the percentage of all identified conserved regions in the human genome that fall into each category. b The percent base-pair match of the DNMT1-dependent regions in mouse with the identified human conserved regions. Pie chart represents the percentage of all conserved regions in the human genome that fall into each category. c The percentage of all conserved regions in the human genome that are located within the promoter, the gene body, or in non-coding intergenic regions. d The top transcription factor binding sites found within all human conserved regions. e The percentage of known germline ASMs in our conserved DNMT1-dependent regions separated by genome