Table 6.
Association between cardiovascular risk and sUA concentration and HUA risk among ABCG2 T allele carriers
| Cardiovascular risk factors | sUA | hyperuricemia | ||
|---|---|---|---|---|
| Beta (SE) | p* | OR 95%CI | p* | |
| Total population | ||||
| BMI | 0.21 (0.60) | 3.40 × 10−8 | 1.42 (1.28–1.56) | 4.25 × 10−12 |
| Hypertension | 0.036 (6.01) | 0.978 | 1.35 (0.85–2.13) | 0.206 |
| TG | 0.24 (3.67) | 6.18 × 10−9 | 1.90 (1.44–2.50) | 4.08 × 10−6 |
| LDL | 0.025 (3.77) | 0.506 | 1.28 (0.94–1.74) | 0.114 |
| HDL | −0.042 (10.76) | 0.311 | 0.69 (0.25–1.90) | 0.471 |
| Male | ||||
| BMI | 0.23 (1.27) | 1.14 × 10−5 | 2.01 (1.62–2.50) | 1.75 × 10−10 |
| Hypertension | 0.022 (7.83) | 0.657 | 1.37 (0.74–2.54) | 0.319 |
| TG | 0.25 (4.72) | 8.95 × 10−6 | 1.88 (1.28–2.74) | 0.001 |
| LDL | 0.015 (5.27) | 0.761 | 1.40 (0.84–2.32) | 0.192 |
| HDL | −0.063 (14.92) | 0.264 | 0.52 (0.11–2.41) | 0.407 |
| Female | ||||
| BMI | 0.20 (1.48) | 0.002 | 1.22 (1.08–1.37) | 0.001 |
| Hypertension | 0.054 (9.45) | 0.370 | 1.27 (0.63–2.55) | 0.498 |
| TG | 0.24 (5.93) | 4.00 × 10−4 | 1.95 (1.26–3.03) | 0.003 |
| LDL | 0.073 (5.44) | 0.231 | 1.30 (0.87–1.41) | 0.208 |
| HDL | 0.025 (15.72) | 0.711 | 0.83 (0.19–3.70) | 0.798 |
*p value for the logistic regression adjusted by age, gender, serum cretinine, BMI, hypertension, TG, LDL, and HDL