Table 1.
Characteristics of subjects stratified by hyperuricemia
| Variables | Total (n = 8163) | Hyperuricemia (n = 1050) | Normouricemia (n = 7113) | P value a |
|---|---|---|---|---|
| Age (years) | 54.13 ± 10.49 | 55.12 ± 10.96 | 53.99 ± 10.41 | 0.001 |
| Males (%) | 3731 (45.71) | 652 (62.10) | 3079 (43.29) | < 0.001 |
| Race, Han (%) | 7936 (97.22) | 1033 (98.38) | 6903 (97.05) | 0.014 |
| Education (%) | 0.716 | |||
| Primary school or below | 4322 (52.95) | 561 (53.43) | 3761 (52.88) | |
| Middle school | 3134 (38.39) | 393 (37.43) | 2741 (38.54) | |
| High school or above | 707 (8.66) | 96 (9.14) | 611 (8.59) | |
| Income, CNY (%) | 0.012 | |||
| ≤ 5000 | 851 (10.43) | 134 (12.76) | 717 (10.08) | |
| 5000–20,000 | 4294 (52.60) | 557 (53.05) | 3737 (52.54) | |
| > 20,000 | 3018 (36.97) | 359 (34.19) | 2659 (37.38) | |
| Physical activity (%) | 0.101 | |||
| Low | 3192 (39.10) | 436 (41.52) | 2756 (38.75) | |
| Middle | 1547 (18.95) | 205 (19.52) | 1342 (18.87) | |
| High | 3424 (41.95) | 409 (38.95) | 3015 (42.39) | |
| Current smoking (%) | 2767 (33.90) | 398 (37.90) | 2369 (33.31) | 0.003 |
| Current drinking (%) | 1734 (21.24) | 332 (31.62) | 1402 (19.71) | < 0.001 |
| Height (cm) | 160.66 ± 8.15 | 162.97 ± 8.45 | 160.32 ± 8.05 | < 0.001 |
| Weight (kg) | 63.49 ± 11.27 | 69.85 ± 12.16 | 62.56 ± 10.82 | < 0.001 |
| BMI (kg/m2) | 24.54 ± 3.61 | 26.26 ± 3.85 | 24.29 ± 3.50 | < 0.001 |
| SBP (mmHg) | 138.68 ± 21.93 | 144.79 ± 23.44 | 137.77 ± 21.55 | < 0.001 |
| DBP (mmHg) | 81.86 ± 11.64 | 86.09 ± 12.63 | 81.24 ± 11.35 | < 0.001 |
| Scr (μmol/L) | 73.80 (66.70–82.20) | 82.70 (74.73–91.80) | 72.80 (66.10–80.70) | < 0.001 |
| eGFR (ml/min per 1.73 m2) | 89.33 ± 15.42 | 81.92 ± 19.13 | 90.42 ± 14.48 | < 0.001 |
| FPG (mmol/L) | 5.60 (5.22–6.10) | 5.72 (5.32–6.35) | 5.58 (5.22–6.06) | < 0.001 |
| TC (mmol/L) | 5.32 ± 1.11 | 5.63 ± 1.28 | 5.27 ± 1.07 | < 0.001 |
| TG (mmol/L) | 1.29 (0.91–1.96) | 1.88 (1.28–2.87) | 1.23 (0.88–1.83) | < 0.001 |
| HDL-C (mmol/L) | 1.34 ± 0.32 | 1.28 ± 0.33 | 1.35 ± 0.32 | < 0.001 |
| LDL-C (mmol/L) | 2.89 ± 0.80 | 3.07 ± 0.88 | 2.87 ± 0.79 | < 0.001 |
| WBC count (109/L) | 6.20 ± 2.06 | 6.61 ± 1.79 | 6.14 ± 2.09 | < 0.001 |
| Lymphocyte count (109/L) | 1.90 (1.60–2.40) | 2.10 (1.70–2.50) | 1.90 (1.60–2.30) | 0.017 |
| Neutrophil count (109/L) | 3.40 (2.70–4.30) | 3.70 (2.90–4.60) | 3.40 (2.60–4.20) | < 0.001 |
| Monocyte count (109/L) | 0.41 (0.30–0.60) | 0.50 (0.40–0.70) | 0.40 (0.30–0.60) | < 0.001 |
| Lipid-lowering drug (%) | 272 (3.33) | 78 (7.43) | 194 (2.73) | < 0.001 |
| History of CVD (%) | 1268 (15.53) | 222 (21.14) | 1046 (14.71) | < 0.001 |
| SUA (μmol/L) | 300.77 ± 85.68 | 452.12 ± 70.17 | 278.43 ± 61.79 | < 0.001 |
| MHR | 0.38 ± 0.25 | 0.45 ± 0.27 | 0.37 ± 0.24 | < 0.001 |
Data are expressed as mean ± standard deviation (SD) or median (interquartile range) and numbers (percentage) as appropriate
Abbreviations: CNY Chinese currency (1CNY = 0.15 USD), BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, Scr serum creatinine, eGFR estimated glomerular filtration rate, FPG fasting plasma glucose, TC total cholesterol, TG triglyceride, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, WBC white blood cell, CVD cardiovascular disease, SUA serum uric acid, MHR Monocyte to high-density lipoprotein ratio
aComparisons for category variables between groups were tested by χ2 test or rank-sum test (ordinal category variables) and comparisons of continuous variables between groups were tested by Student’s t-test or Mann-Whitney test