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. Author manuscript; available in PMC: 2021 May 1.
Published in final edited form as: J Thorac Cardiovasc Surg. 2019 Jun 18;159(5):1825–1835.e2. doi: 10.1016/j.jtcvs.2019.06.017

Figure 2. EPC-EVs promote a robust angiogenic response from chronically hypoxic HUVECs.

Figure 2.

HUVECS were exposed to chronic hypoxia (7 days, 5% O2) to mimic an ischemic environment. Naive and preconditioned HUVECs were incubated with EVs in 5% O2 for 14 hours. Chronically hypoxic HUVECs demonstrated increased vascular tubule mesh formation compared to the naive group (p=0.049).