Fig. 1.
A conceptual flowchart of topographic mapping of multiple variables for DBS optimization. a During insertion of the each nth electrode, selected parameters (p) can be quantitatively evaluated, denoted as pn. b Postoperatively, the position of each electrode contact can be calculated from postoperative MRI. c Over all N study patients, a collection of each measurement and the corresponding electrode contact position can be represented by a 4 × N array, Pn. d Array Pn is submitted to the roving window interpolation (RWI) algorithm to construct relational topographies of these parameters in selected planes. e Similarly, Pn arrays can be formed from measurements taken at sequential postoperative follow-up intervals, creating a visual time line of the measured effects.