Table 1.
Pathogens or insects targeting the JAZ-MYC2 hub.
| Species | Effectors-Plant Targets | Mechanism | Reference |
|---|---|---|---|
| Virus | |||
| Tomato yellow leaf curl China virus (begomovirus) | βC1-MYC2 | Subvert defense gene activity, compromise terpene synthase | [77] |
| Tomato yellow leaf curl virus (begomovirus) | C2-JAZ1 | Compromise JAZ1 degradation, inhibit downstream gene regulated defense | [78] |
| Tomato spotted wilt orthotospovirus (tospovirus) | NSs-MYC2 | Directly interact with MYCs to disable JA-mediated host defenses against the thrip vector | [79] |
| Cucumber mosaic virus (bromovirus) | 2b-JAZ | Repress the JA-induced degradation of JAZ proteins | [80] |
| Bacterium and Fungal | |||
| Pseudomonas syringae pv. tabaci (Pta) 11528 | HopX1-JAZ | Encode a cysteine protease to promote the degradation of JAZ proteins | [81] |
| Pseudomonas syringae strain A2 | HopZ1a-JAZ | JAZs can be acetylated by HopZ1a through putative acetyltransferase activity. | [82] |
| Pseudomonas syringae | AvrB-JAZ | Induce the COI1–JAZs interactions and the degradation of multiple JAZ proteins | [83] |
| Laccaria bicolor | MiSSP7-JAZ | Interact with and stabilize JAZ proteins against JA-Ile mediated degradation | [84] |
| Pseudomonas syringae | HopBB1-JAZ | Utilize JAZ3 to target TCP14 to the SCFCOI1 degradation complex | [85] |
| Pseudomonas fluorescens WCS417r | ? /-MYC2 | Utilize MYC2 to enhance JA-mediated induced systemic resistance against pathogens and insect herbivores | [86] |
| Pseudomonas syringae | COR-COI1/JAZ | Depredate JAZ, activate the host’s JA signaling pathway to suppress salicylic acid to promote bacterial virulence | [87] |
| Insect | |||
| Helicoverpa armigera | HARP1-JAZ | Directly interact with JAZ to prevent its COI1-mediated degradation | [70] |
| Pieris brassicae | egg extract-MYC | Diminished MYC protein levels in a SA-dependent manner | [57] |