Control leaves with sterile distilled water (A) and MeOH (4% v/v) (a); necrotic areas produced by (−)-(R)-mellein (1), (±)-botryoisocoumarin A (2), (−)-(3R,4R)-4-hydroxymellein (3), (−)-(3R,4S)-4-hydroxymellein (4), (−)-terpestacin (5), and (+)-neoisocoumarin (6) on tomato leaves.