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Effect of suberanilohydroxamic acid (SAHA) and Ro5-3335 treatment on the human immunodeficiency virus type 1 (HIV-1) long terminal repeat (LTR). TZMbl cells were cultured for 48 h in medium containing indicated concentrations of SAHA in the presence or absence of 50μM of Ro5-3335. Cells were harvested for chromatin immunoprecipitation (ChIP) using antibodies against (A) histone H3 acetylated at lysine 9 (H3K9ac), (B) RUNX1, (C) core binding factor-β (CBF-β) or (D) STAT5.
