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. 2020 Feb 9;12(2):191. doi: 10.3390/v12020191

Figure 6.

Figure 6

Effect of Alprazolam on HIV-1 transcription in TZMbl. TZMbl cells were seeded in 96-well plates and treated with (A) different concentrations of BDZs or (B) a combination of Alprazolam and SAHA. (C) TZMbl cells were transfected with pCMV-Tat or pUC19 control plasmid and treated with 10 µM of the indicated BDZ. At 48 h after treatment, the cells were lysed and equal mass of protein lysates were used to determine the production of luciferase from the integrated LTR. Results are shown as the relative luciferase activity compared to control. Each data point is the average of three replicates. * P ≤ 0.05, ** P ≤ 0.04, *** P ≤ 0.0001.