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. 2020 Feb 14;12(2):211. doi: 10.3390/v12020211

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Unlike metagenomics (a), target HTS takes on an extra step of hybridization enrichment (b) and/or target amplification (c), during which the concentration of selected sequences is increased.