FIGURE 4.

Reduced arterial diameter and RBC velocity after mTBI. (A) Changes in cerebral arterial morphology at different time points after mTBI in sham and injury groups. In comparison to the sham group, arteries of the mTBI group showed obvious constriction between 0.5 and 6 h post-mTBI. (B) Arterial diameters became smaller between 0.5 and 6 h post-injury (p < 0.05 at all time points when compared with the same time points of the sham groups, repeated measure ANOVA), and partially recovered to baseline level at one day post-mTBI (p > 0.05). (C) Consistent with the reduced diameter, arterial RBC velocity also significantly decreased between 0.5 and 6 h and recover to thebaseline level at 1 day following mTBI (*p < 0.05).