Figure 2.

Expression of collagen type III and elastin. Western analysis of (A) collagen type III, (B) elastin expression and (C) collagen type III/elastin ratio in aortas from Ins2^Akita, ApoE^−/− and Ins2^Akita: ApoE^−/− mice and from sex‐ and age‐matched (3 months old) C57BL/6 non‐diabetic control mice, with GAPDH serving as a loading control. The bar graph represents for each value the mean ± SD from 3 separate experiments. *P < .05 vs C57BL/6 control mice; #P < .05 vs ApoE^−/− mice; §P < .05 vs Ins2^Akita mice and ApoE^−/− mice; N = 8 mice/group