Figure 6.

Protection of the Notch1‐MFN1/Drp1 axis on the post‐ischaemic recovery of myocardial performance is associated with the preservation of the mitochondrial structure. A, Representative traces and summarized data of LV pressure (LVP) during ischaemia‐reperfusion (I/R) in isolated rat hearts from indicated groups. B, Representative images and analysis of the infarct size in isolated I/R (30 min/2 h) hearts. C, The mitochondrial fusion and fission markers were analysed by Western blot. D, The structure of mitochondria was observed by electron microscopy. All data are means ± SEM *P < .05, **P < .01 and ***P < .001, with the indicated group