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. 2020 Jan 30;24(5):2901–2916. doi: 10.1111/jcmm.14884

Figure 7.

Figure 7

VB promotes cell apoptosis of U87 cells. A, mRNA expression of Caspase‐3, Bax and Bcl‐2; B, the protein expression of Caspase‐3, Bax and Bcl‐2, and the ratio of Cleaved caspase‐3/Caspase‐3 in U87 cells after transfection; C, the mRNA expression of Caspase‐3, Bax and Bcl‐2; D, the protein expression of Caspase‐3, Bax and Bcl‐2, and the ratio of Cleaved caspase‐3/Caspase‐3 in U87 cells after transfection; E, apoptosis rate of U87 cells transfected with let‐7g‐5p mimic, let‐7g‐5p inhibitor alone or in the presence of VB; F, apoptosis rate of U87 cells transfected with HMGA2 vector alone or in the presence of let‐7g‐5p mimic, si‐HMGA2 alone or in the presence of let‐7g‐5p inhibitor; * P < .05 vs the blank group and the NC group; & P < .05 vs the NC mimic group; # P < .05 vs the NC inhibitor group. All measurement data were summarized as mean ± SD. Comparisons among multiple groups were performed with one‐way analysis of variance. The experiment was repeated three times independently