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. 2020 Feb 12;12(2):425. doi: 10.3390/polym12020425

Table 3.

Aerodynamic characteristics of ChS/INH/RFB (10/1/0.5, w/w) microparticles (mean ± SD, n = 3). Different letters indicate statistically significant difference within the same parameter (p < 0.05).

Microparticles Powder Emitted Dose (%) Drug MMAD (µm) GSD (µm) FPD (mg) FPF (%)
ChS/INH/RFB (ethanol) 90.9 ± 1.0a INH 3.8 ± 0.1b 1.9 ± 0.1c 3.1 ± 0.3d 43.7 ± 2.4g
RFB 3.9 ± 0.1 b 2.0 ± 0.1c 1.5 ± 0.1e 42.6 ± 1.7g
ChS/INH/RFB (HCl) 89.6 ± 1.8a INH 4.0 ± 0.2 b 2.0 ± 0.0c 2.9 ± 0.1d 35.0 ± 1.7h
RFB 4.0 ± 0.3 b 2.1 ± 0.1c 1.2 ± 0.1f 34.0 ± 3.7h

FPD: fine particle dose; FPF: fine particle fraction; GSD: geometric standard deviation; MMAD: mass median aerodynamic diameter.