SWAN-venule acquired in 3 subjects with RRMS. A, Examples of lesions with central veins in 3 planes. In each raw, arrows point the same lesion in three different planes. An example of a deep white matter (DWM) lesion, a periventricular lesion, and a juxtacortical lesion shows the central vein in 3 different planes. B, Example of 2 deep white matter lesions that developed along the same vein. PV indicates periventricular; JC, juxtacortical.