Table 5:
Ischemic Time for Donation After Cardiocirculatory Death Hearts, by Procurement Technique
| Outcome | DCD Procurement Technique, MD (IQR) | P | |
|---|---|---|---|
| DPP (min) | NRP (min) | ||
| Functional warm ischemic timea | 26 (23–31) | 17 (15–17) | < .001 |
| Donation withdrawal ischemic timeb | 37 (33–42) | 24 (21–28) | < .003 |
| Perfusion time on portable normothermic cardiac perfusion system | 241 (210–280) | 170 (140–179) | < .003 |
Abbreviations: DCD, donation after cardiocirculatory death; DPP, direct procurement and perfusion; IQR, interquartile range; MD, median; NRP, normothermic regional reperfusion.
a
Measured from when systolic blood pressure is < 50 mmHg, thus organs are presumed to be poorly perfused. Functional warm ischemic time is considered to be ended upon reperfusion on a portable normothermic cardiac perfusion system.
b
Measured from withdrawal of life-sustaining therapy. Donation withdrawal ischemic time is considered to be ended upon reperfusion on a portable normothermic cardiac perfusion system.
Source: Messer et al, 2017.36