Figure 3. A representative SPARQL query that integrates data from multiple data resources and annotation types.

This example integrative query incorporates data on genetic associations to disease, Gene Ontology annotations for cellular compartment, protein target information for compounds, pathway data, and protein domain information. Specifically, this query (depicted schematically at right) retrieves genes that are (i) associated with a respiratory system disease, (ii) that encode a membrane-bound protein, and (iii) that sit within the same biochemical pathway as (iv) a second gene encoding a protein with a serine-threonine kinase domain and (v) a known inhibitor, and reports a list of those inhibitors. Aspects related to Disease Ontology in blue; aspects related to biochemistry in red/orange; aspects related to chemistry in green. Properties are shown in italics. Real-time query results can be viewed at https://w.wiki/6pZ.