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. 2020 Mar 17;9(3):e01120. doi: 10.1002/cti2.1120

Figure 2.

Figure 2

The mucociliary escalator. (a) MUC5B is the predominant mucin throughout the airway, and the majority is secreted distally. (b) MUC5AC is predominantly secreted in the proximal airway. (c) The mucus (gel) layer is made up of MUC5B, MUC5AC, water and ions. (d) The periciliary layer consists of the membrane‐bound mucins, water and ions.