Table 2.
Individual MS Patient Characteristics
Patient | Sex | APOE ε4 Status | MS Phase | MS Onset Age, yr | DMT | PET Imaging Age, yr | MCI | PiB SUVra | AV1451 SUVra |
---|---|---|---|---|---|---|---|---|---|
1 | F | + | Progressive | 29 | − | 80 | − | 1.39 | − |
2 | F | − | Relapsing | 33 | − | 77 | + | 1.23 | 1.32 |
3 | F | − | Progressive | 40 | − | 75 | − | 1.33 | 1.17 |
4 | F | + | Relapsing | 46 | − | 74 | − | 1.42 | − |
5 | F | − | Relapsing | 47 | − | 69 | + | 1.38 | 1.26 |
6 | F | − | Progressive | 66 | − | 67 | − | 1.35 | 1.06 |
7 | M | − | Progressive | 49 | IFNb 1a | 64 | − | 1.42 | 1.20 |
8 | M | − | Progressive | 51 | − | 63 | − | 1.38 | − |
9 | M | + | Progressive | 53 | − | 63 | + | 1.23 | 1.17 |
10 | F | − | Relapsing | 32 | − | 63 | − | 1.31 | 1.27 |
11 | F | − | Relapsing | 35 | − | 58 | − | 1.55 | 1.18 |
12 | F | − | Relapsing | 52 | DMF | 57 | − | 1.40 | 1.29 |
13 | F | + | Relapsing | 43 | IFNb 1a | 57 | − | 1.39 | 1.23 |
14 | M | + | Relapsing | 46 | IFNb 1a | 57 | − | 1.24 | 1.16 |
15 | M | − | Relapsing | 42 | IFNb 1a | 53 | − | 1.33 | − |
16 | F | − | Relapsing | 33 | − | 45 | − | 1.25 | 1.14 |
Alzheimer disease signature PiB and AV1451 SUVrs are displayed in the table.
DMF = dimethyl fumarate; DMT = disease‐modifying treatment; F = female; IFNb 1a = interferon beta 1a; M = male; MCI = mild cognitive impairment; MS = multiple sclerosis; PiB = Pittsburgh compound B; SUVr = standardized uptake value ratio.