Table 1: Patient Metrics for Isolated Cardiomyocyte Studies.

Metrics from human hearts used for intact myocyte mechanical assays. A total of 7 non-failing and 5 failing hearts were included in the study. Of these, 10 hearts were used in studies of freshly isolated cells (colchicine and parthenolide experiments) and 8 were used for myocyte culturing experiments (TTL overexpression). Five hearts were used for the comparison between freshly isolated and cultured cells (c.f. Supplemental Excel File). Data presented as mean +− 1SD, with unadjusted P-value for two-sample T-test comparing NF and HFrEF groups listed adjacent to means.

Etiology	Non-Failing	HFrEF	Unadjusted P-Value
Gender	3M, 4F	3M, 2F
Age	58.4 ± 7.8	41.6 ± 15.9	0.035
LVMI	106.7 ± 21.3	129.6 ± 22.1	0.1
LVEF	65.8 ± 3.8	16.6 ± 5.3	2.20E-08