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. Author manuscript; available in PMC: 2021 Apr 1.
Published in final edited form as: J Nutr Biochem. 2019 Dec 16;78:108316. doi: 10.1016/j.jnutbio.2019.108316

Figure 2 – Dietary fructose and copper levels influence hepatic and serum bio-metals (ppb) for all dietary groups and sexes (n=6).

Figure 2 –

Numbers (1-4) indicate groups with means significantly different from the labeled group.

A) Male rats displayed significant differences (P<0.005) in serum Cu between all dietary groups, except between the 30% CuD (mean=52.933 ppb) and 0% CuD (mean=154.382 ppb) groups (P=0.059). Female rats had no difference in circulating Cu levels between any of the dietary groups.

B) Hepatic Cu levels were changed (P<0.005) in male rats by low dietary copper, while females displayed no change in hepatic Cu levels in response to either dietary fructose or copper.

C) Serum Mo levels in males were significantly lower (P<0.05) in the 30% CuD group when compared to both non-supplemented groups. Changes in fructose and/or Cu did not induce changes in circulating Mo in female rats.

D) Hepatic Mo levels in males were significantly lower (P<0.01) in the 30% CuD group when compared to both non-supplemented groups paralleling circulating Mo levels. No difference was seen between any of the female groups hepatic Mo levels.

E) Hepatic Zn increased in male rats fed excess fructose (P < 0.05), while Zn was not impacted by dietary Cu. The male 0% CuA group had significantly higher hepatic zinc when compared to the 30% CuD group. Female rats displayed no major changes to hepatic Zn in response to dietary treatments.