Table 2.
Duration of hypoglycemia according to age, duration of diabetes, estimated glomerular filtration rate, body mass index, sulfonylurea dose or diabetic complications
Duration (min/h) | Duration (min/h) | P | |
---|---|---|---|
Hypoglycemia of <54 mg/dL | |||
Age (years) | <75 | ≥75 | |
0.45 (n = 178) | 0.81 (n = 91) | 0.11 | |
Duration of diabetes (years) | <15 | ≥15 | |
0.29 (n = 111) | 0.80 (n = 151) | <0.05 | |
eGFR (mL/min/1.73 m2) | <60 | ≥60 | |
0.64 (n = 94) | 0.55 (n = 171) | 0.68 | |
BMI (kg/m2) | <25 | ≥25 | |
0.65 (n = 68) | 0.45 (n = 199) | 0.38 | |
Gliclazide (mg/day) | ≤20 | >20 | |
0.23 (n = 58) |
0.84 (n = 27) |
<0.05 | |
Glimepiride (mg/day) | ≤1 | >1 | |
0.42 (n = 130) | 1.5 (n = 38) | <0.01 | |
(+) | (−) | ||
Diabetic retinopathy | 0.78 (n = 88) | 0.48 (n = 173) | 0.18 |
Diabetic nephropathy | 0.50 (n = 103) | 0.61 (n = 66) | 0.58 |
Diabetic neuropathy | 0.81 (n = 102) | 0.42 (n = 167) | 0.07 |
Macrovascular complications | 0.57 (n = 69) | 0.54 (n = 200) | 0.89 |
Hypoglycemia of <70 mg/dL | |||
Age (years) | <75 | ≥75 | |
2.2 (n = 178) | 3.0 (n = 91) | 0.09 | |
Duration of diabetes (years) | <15 | ≥15 | |
1.7 (n = 111) | 3.0 (n = 151) | <0.01 | |
eGFR (mL/min/1.73 m2) | <60 | ≥60 | |
3.1 (n = 94) | 2.1 (n = 171) | 0.06 | |
BMI (kg/m2) | <25 | ≥25 | |
2.6 (n = 68) | 2.2 (n = 199) | 0.32 | |
Gliclazide (mg/day) | ≤20 | >20 | |
1.6 (n = 58) |
4.2 (n = 27) |
<0.01 | |
Glimepiride (mg/day) | ≤1 | >1 | |
1.8 (n = 130) | 4.2 (n = 38) | <0.01 | |
(+) | (−) | ||
Diabetic retinopathy | 2.9 (n = 88) | 2.3 (n = 173) | 0.26 |
Diabetic nephropathy | 2.8 (n = 103) | 2.2 (n = 166) | 0.26 |
Diabetic neuropathy | 2.9 (n = 102) | 2.2 (n = 167) | 0.12 |
Macrovascular complications | 2.5 (n = 69) | 2.4 (n = 200) | 0.74 |
Data are adjusted by glycated hemoglobin level. P < 0.05 was considered significant. BMI, body mass index; eGFR, estimated glomerular filtration rate.
[Correction added on 2 October, after first online publication: Some alignments in the table have been amended.]