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. 2019 Sep 17;11(2):417–425. doi: 10.1111/jdi.13132

Table 2.

Duration of hypoglycemia according to age, duration of diabetes, estimated glomerular filtration rate, body mass index, sulfonylurea dose or diabetic complications

  Duration (min/h) Duration (min/h) P
Hypoglycemia of <54 mg/dL
Age (years) <75 ≥75
0.45 (= 178) 0.81 (= 91) 0.11
Duration of diabetes (years) <15 ≥15
0.29 (= 111) 0.80 (= 151) <0.05
eGFR (mL/min/1.73 m2) <60 ≥60
0.64 (= 94) 0.55 (= 171) 0.68
BMI (kg/m2) <25 ≥25
0.65 (= 68) 0.45 (= 199) 0.38
Gliclazide (mg/day) ≤20 >20

0.23 (= 58)

0.84 (= 27)

<0.05
Glimepiride (mg/day) ≤1 >1
0.42 (= 130) 1.5 (= 38) <0.01
  (+) (−)  
Diabetic retinopathy 0.78 (= 88) 0.48 (= 173) 0.18
Diabetic nephropathy 0.50 (= 103) 0.61 (= 66) 0.58
Diabetic neuropathy 0.81 (= 102) 0.42 (= 167) 0.07
Macrovascular complications 0.57 (= 69) 0.54 (= 200) 0.89
Hypoglycemia of <70 mg/dL
Age (years) <75 ≥75
2.2 (= 178) 3.0 (= 91) 0.09
Duration of diabetes (years) <15 ≥15
1.7 (= 111) 3.0 (= 151) <0.01
eGFR (mL/min/1.73 m2) <60 ≥60
3.1 (= 94) 2.1 (= 171) 0.06
BMI (kg/m2) <25 ≥25
2.6 (= 68) 2.2 (= 199) 0.32
Gliclazide (mg/day) ≤20 >20

1.6 (= 58)

4.2 (= 27)

<0.01
Glimepiride (mg/day) ≤1 >1
1.8 (= 130) 4.2 (= 38) <0.01
  (+) (−)  
Diabetic retinopathy 2.9 (= 88) 2.3 (= 173) 0.26
Diabetic nephropathy 2.8 (= 103) 2.2 (= 166) 0.26
Diabetic neuropathy 2.9 (= 102) 2.2 (= 167) 0.12
Macrovascular complications 2.5 (= 69) 2.4 (= 200) 0.74

Data are adjusted by glycated hemoglobin level. < 0.05 was considered significant. BMI, body mass index; eGFR, estimated glomerular filtration rate.

[Correction added on 2 October, after first online publication: Some alignments in the table have been amended.]